Research:

Publications:

RESEARCH PUBLICATIONS:

1.     T Nargis, K Kumar, A R Ghosh, A Sharma, D Rudra, D Sen, S Chakrabarti, S Mukhopadhyay, D Ganguly, P Chakrabarti. KLK5 induces shedding of DPP4 from circulatory Th17 cells in Type 2 Diabetes. Molecular Metabolism, 2017;  6 (11): 1529-1539. Featured Article.

2.     AR Ghosh, R Bhattacharya, S Bhattacharya, T Nargis, O Rahaman, P Duttagupta, D Raychaudhuri, CS Liu, S Roy, P Ghosh, S Khanna, T Chaudhuri, O Tantia, S Haak, S Bandyopadhyay, S Mukhopadhyay, P Chakrabarti, D Ganguly. Adipose recruitment and activation of plasmacytoid dendritic cells fuel metaflammation. Diabetes, 2016; 65(11): 3440-3452.

3.     J Sarkar#, T Nargis#, O Tantia, S Ghosh, P Chakrabarti. Plasma dipeptidyl peptidase-4 (DPP4) activity is an obesity-independent parameter for glycemic deregulation in type 2 diabetes patients. Frontiers in Endocrinology, 2019; 10: 505. #equal authorship.

4.     C Selvan, D Dutta, A Thukral, T Nargis, M Kumar, S Mukhopadhyay, S Chowdhury. Neck height ratio is an important predictor of metabolic syndrome among Asian Indians. Indian Journal of Endocrinology and Metabolism, 2016; 20(6): 831-837.

5.     J Sarkar, S K Maity, T Nargis, D B Ray, P Chakrabarti. Impaired compensatory hyperinsulinemia with increasing body weight among non-obese type 2 diabetes: A cross-sectional study. Therapeutic Advances in Endocrinology and Metabolism, 2019; 10: 1-10.

6.     I Ghosh, P Mukhopadhyay, K Das, B Anne, S A Mondal, M Basu, T Nargis, K Pandit, P Chakrabarti, S Ghosh. Incretins in Fibrocalculous Pancreatic Diabetes: A unique subtype of Type 3c Diabetes. Journal of Diabetes, 2021; 13: 506–511.

7.     Y Xu, P C Miller, C KL Phoon, M Ren, T Nargis, S Rajan, M M Hussain, M Schlame. LPGAT1 controls the stearate/palmitate ratio of phosphatidylethanolamine and phosphatidylcholine in sn-1 specific remodeling. Journal of Biological Chemistry, 2022; 298(3): 101685.

8.     B Barkondaj, T Nargis, P Chakrabarti, S Mukhopadhyay, K Biswas, D Ganguly, C Chaterjee, N Sengupta, A Hazra. An Observational Study showing Dipeptidyl Peptidase-4 (DPP-4) Activity and Gene Expression Variation in Chronic Liver Disease (CLD) Patients from a Tertiary Care Hospital of Eastern India. Indian Journal of Endocrinology and Metabolism, 2022; 26(3): 245–251.

9.     T Nargis, A R Piñeros, S C May, S A Tersey, R G Mirmira. Protocol to isolate immune cells from mouse pancreatic lymph nodes and whole pancreas for mass cytometric analyses. STAR Protocols, 2022; 4(1):101938. DOI: 10.1016/j.xpro.2022.101938.

10.  T Nargis, X Lin, E Giordano, L Ijaz, S Suhail, E M Gurzenda, D Kiefer, L Quadro, N Hanna, M M Hussain. Characterization of lipoproteins in human placenta and fetal circulation as well as gestational changes in lipoprotein assembly and secretion in human and mouse placentas. Biochim Biophys Acta Mol Cell Biol Lipids, 2023; 1868(9): 159357.

11.  E Ermis, T Nargis, K Webster, S A Tersey, R M Anderson, R G Mirmira. Leukotriene B4 receptor 2 (BLT2) governs macrophage migration during tissue inflammation. Journal of Biological Chemistry, 2024; 300(1): 105561.

12.  C Muralidharan, F Huang, J R Enriquez, J E Wang, J B Nelson, T Nargis, S C May, A Chakraborty, K T Figatner, S Navitskaya, C M Anderson, V Calvo, D Surguladze, M J Mulvihill, X Yi, S Sarkar, S A Oakes, B M Webb-Robertson, E K Sims, K A Staschke, D L Eizirik, E S Nakayasu, M E Stokes, S A Tersey, R G Mirmira. Inhibition of the eukaryotic initiation factor-2-α kinase PERK decreases risk of autoimmune diabetes in mice. Journal of Clinical Investigation, 2024 Jun 18.

13.  T Nargis, C Muralidharan, J R. Enriquez, J E. Wang, K Kaylan, A Chakraborty, S Pratuangtham, K Figatner, J B. Nelson, S C. May, J L. Nadler, M B. Boxer, D J. Maloney, S A. Tersey and R G. Mirmira. 12-Lipoxygenase inhibition delays onset of autoimmune diabetes in human gene replacement mice. JCI Insight,2024 Nov 10.1172/jci.insight.185299.

14.  K Kaylan^#, T Nargis^#, K Figatner, J E. Wang, S Pratuangtham, A Chakraborty, I Casimiro, J L. Nadler, M B. Boxer, D J. Maloney, R M. Anderson, R G. Mirmira, and S A. Tersey. 12-Lipoxygenase inhibition improves glycemia and obesity-associated inflammation in male human gene replacement mice. Endocrinology 2025 Apr 5: DOI: 10.1210/endocr/bqaf069  ^#Authors contributed equally.

15.  J E Wang, C Muralidharan, A A Puente, T Nargis, J R Enriquez, R M Anderson, R G Mirmira, S A Tersey. The integrated stress response promotes macrophage inflammation and migration in autoimmune diabetes. Cell Communication and Signaling 2025: DOI.org/10.1186/s12964-025-02372-z

16.  K Kaylan, C Checkcinco, J R Enriquez, T Nargis, E Elliott, A A Puente, J E Wang, M Walsh, J B Nelson, A Kulkarni, C Muralidharan, S C May, R M Anderson, R G Mirmira, S A Tersey. The G Protein-Coupled Receptor GPR31 Promotes Pro-inflammatory Responses in Pancreatic Islets and Macrophages. doi: https://doi.org/10.1101/2025.10.02.680021

REVIEW ARTICLES:

1.     T Nargis and P Chakrabarti. Significance of circulatory DPP4 activity in metabolic diseases. IUBMB LIFE, 2018; 70(2):112-119 Featured Article.

2.     L Quadro, E Giordano, B K. Costabile, T Nargis, J Iqbal, Y Kim, L Wassef and M. M Hussain. Interplay between beta-carotene and lipoprotein metabolism at the maternal-fetal barrier. Biochim Biophys Acta Mol Cell Biol Lipids, 2020; 1865(11): 158591.

Recognition:

• Research grant from Research Society of Study of Diabetes (RSSDI) for study of diabetes in India , 2014
• An international travel award (Go Everywhere Travel Grant Program) from R&D system Bio-Techne., 2017
• Poster awardees at Janet Rowley Research Day, University of Chicago, USA., 2024
• Poster awardees at Diabetes Day, University of Chicago, USA., 2024
• Inspire Faculty funded by Department of Science and Technology (DST), 2025

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