Now showing items 1-2 of 2
Acetaminophen induced renal injury via oxidative stress and TNF-alpha production: Therapeutic potential of arjunolic acid
(ELSEVIER IRELAND, 2010-01-31)
Acetaminophen (APAP) causes acute and chronic renal failure. The mechanisms leading to hepatic injury have been extensively studied, but the molecular mechanisms regarding APAP-induced nephro-toxicity are poorly defined. ...
Protection of acetaminophen induced mitochondrial dysfunctions and hepatic necrosis via Akt-NF-kappa B pathway: Role of a novel plant protein
(ELSEVIER IRELAND, 2009-01-27)
Oxidative stress is a major cause of drug induced hepatic diseases. The present study aims to investigate the antioxidative signaling mechanism of a protein isolated from the herb, Cajanus indicus against acetaminophen ...