Browsing by Subject "-CpG-islands"

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Demethylation of (Cytosine-5-C-methyl) DNA and regulation of transcription in the epigenetic pathways of cancer development

Patra, Samir Kumar; Patra, Aditi; Rizzi, Federica; Ghosh, Tapash Chandra; Bettuzzi, Saverio (SPRINGER, 2008-06)

Cancer cells and tissues exhibit genome wide hypomethylation and regional hypermethylation. CpG-methylation of DNA ((Me)CpG-DNA) is defined as the formation of a C-C covalent bond between the 5'-C of cytosine and the -CH(3) ...